The Stergachis lab is located in the Division of Medical Genetics and the Department of Genome Sciences at the University of Washington

Our group is motivated by the question of how alterations in gene regulation contribute to human disease. Genomics is rapidly emerging as a cornerstone of medicine, yet our current understanding of the human genome remains largely limited to only 1% of the human genome, which is the portion that codes for proteins. By contrast, genetic changes in the other 99% of the human genome that alter when and where proteins are produced remain poorly understood. Our group aims to overcome this challenge by developing and applying novel epigenomic tools to study the impact of non-coding and epigenetic variation on human disease.